We are proud to announce that Professor Naresh Sriram, has co‑authored an important review article titled “Radiation‑Induced Modulation of Salivary Statherin in Oral Cancer: Current Evidence and Clinical Implications”, recently published in the International Journal of Health Sciences and Pharmacy.
The publication provides a comprehensive analysis of how radiotherapy — a cornerstone in the treatment of oral cancer — influences levels of salivary statherin, a key protein involved in oral health through calcium regulation, enamel protection, and mouth lubrication. Changes in salivary protein profiles have significant clinical implications for patients undergoing radiation, particularly in relation to dry mouth, enamel demineralization, microbial imbalances, and overall oral quality of life.
The review synthesizes current evidence on:
Radiation‑associated effects on salivary gland function and protein secretion,
Molecular mechanisms linking radiation exposure to reductions in salivary statherin,
The potential of statherin as a biomarker for radiation-induced glandular damage, and
Future directions for research aimed at improving clinical monitoring and therapeutic strategies for oral cancer patients.
By contextualizing these findings within the broader understanding of radiation effects on salivary composition — an area where recent research highlights complex changes in saliva following head and neck radiotherapy — this article contributes valuable insights that may help shape future clinical practice and research priorities.
This achievement highlights Professor Naresh Sriram’s leadership in academic research and the University’s dedication to impactful scholarship.
The full article is available here:
🔗 Radiation‑Induced Modulation of Salivary Statherin in Oral Cancer: Current Evidence and Clinical Implications